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St Edmund Hall Magazine –
From the Chapel
The Chapel, at the heart of the Hall’s vibrant community, continues to offer a space of encounter, welcome, and quiet contemplation. We meet the Divine in word and music, and ourselves, as we take time to step out of routine, to celebrate, commemorate, or simply be.
This past year has been marked by change, which has shaped the life of the Chapel and its mission. The College community said goodbye to the Revd Dr Zachary Guiliano, former Chaplain and Career Development Research Fellow in Early Medieval History. Our thanks for his care of, and service to, the College community. We mourned the loss of Dr James Whitbourn, our Director of Music. A small service was held in May, at which present and former members of the Choir were in attendance. A College memorial service followed on Saturday 1 June, which was attended by members of the Hall and University community, as well as Dr Whitbourn’s family. Our gratitude to James remains undiluted by
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Jiri Neuzil and colleagues review the processes and mechanisms that underlie horizontal mitochondrial transfer (HMT) and the metabolic consequences of HMT in cells.
Abstract
Mammalian genes were long thought to be constrained within somatic cells in most cell types. This concept was challenged recently when cellular organelles including mitochondria were shown to move between mammalian cells in culture via cytoplasmic bridges. Recent research in animals indicates transfer of mitochondria in cancer and during lung injury in vivo, with considerable functional consequences. Since these pioneering discoveries, many studies have confirmed horizontal mitochondrial transfer (HMT) in vivo, and its functional characteristics and consequences have been described. Additional support for this phenomenon has come from phylogenetic studies. Apparently, mitochondrial trafficking between cells occurs more frequently than previously thought and contributes to diverse processes including bioenerge